South Carolina declared an end on Monday to the largest measles outbreak in the United States in more than 35 years — a six-month crisis that infected nearly 1,000 people, hospitalized at least 21, and shook the confidence of public health officials nationwide.
The South Carolina Department of Public Health confirmed that 42 consecutive days had passed without a new confirmed case linked to the outbreak — the threshold that indicates a chain of transmission has been permanently broken. The outbreak began in October 2025 in Spartanburg County, a largely unvaccinated pocket of the state’s Upstate region, seeding itself through private schools and church communities before health officials could
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