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NFL odds, Week 2: Opening lines include 49ers as biggest favorite

Greggory Tripp
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San Francisco 49ers v Miami Dolphins
San Francisco 49ers v Miami Dolphins

MIAMI GARDENS, FLORIDA – DECEMBER 22: Brock Purdy #13 of the San Francisco 49ers looks on before the play during the second quarter against the Miami Dolphins at Hard Rock Stadium on December 22, 2024 in Miami Gardens, Florida. (Photo by Megan Briggs/Getty Images)
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Greggory Tripp
Greggory Tripp
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