Week 5 of the 2025 NFL season is here and we’ll be treated to an NFC West showdown on Thursday night featuring the San Francisco 49ers heading down the coast to visit the Los Angeles Rams. L.A. enters as a 7-point home favorite, with an over/under of 46.5. Both of these teams enter this matchup at 3-1 on the year and will try to maintain their status at the top of a very competitive divisional race.
Below, we will take a look at the best DFS plays for this Thursday night showdown.
Captain’s Picks
Christian McCaffrey, RB, San Francisco 49ers (FLEX $13,200, CPT $19,800)
McCaffrey is the highest priced player in this matchup
→ Continue reading at SB Nation
