Fast weight-loss methods have never been easier or more readily available, but they come at a cost — and for the young, dangerously experimenting protagonist of “Saccharine,” that’s higher and more damaging than a monthly Wegovy subscription. The third feature from writer-director Natalie Erika James is a timely one, tapping into a current medical phenomenon while also aligning itself with a run of recent genre fare (most notably the 2024 sleeper “The Substance”) predicated on female body insecurity. Real-life horror of one’s own body is the most insidious kind of body horror at play here, though James’ film offers a measure of the gorily fantastical stuff too.
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